Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

Hey guys, this weeks article is an important one because it shows that both hybrid strains and ancient stains of wheat are toxic to not only those with celiac disease but to those with non-celiac gluten sensitivity as well. Here are some direct points the article made:

  • Increased intestinal permeability after gliadin exposure occurs in all individuals. Following gliadin exposure, both patients with gluten sensitivity and those with active celiac disease demonstrate a greater increase in intestinal permeability than celiacs in disease remission. A higher concentration of IL-10 was measured in the media exposed to control explants compared to celiac disease in remission or gluten sensitivity.
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Migraine Associated with Gastrointestinal Disorders: Review of the Literature and Clinical Implications

Migraine Associated with Gastrointestinal Disorders: Review of the Literature and Clinical Implications

Hey guys, when I think of migraines, I just think of a tremendous amount of pain. Headaches were always something of an issue for me as a child and then I made the leap to official migraines in my early twenties and talk about debilitating and ouchy. Yes there are tons of medication out there for migraines; however lucky for me I only had four to six monsters a year, my then neurologist suggested I take medication 365 days a year to prevent them and that just wasn’t me, so I had to find alternative means to deal with them. One way was to steer clear of certain foods that would trigger headaches like dairy, processed meats and chocolate… don’t remember wheat, barley or rye ever being on any of those lists. How about you? 

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Intestinal Permeability - A New Target for Disease Prevention and Therapy

Intestinal Permeability - A New Target for Disease Prevention and Therapy

Hey guys, thought this was a great article that included some much needed definitions as to what exactly intestinal permeability and intestinal barrier are. In addition, this article goes into great detail explaining many more points that I could briefly mention here about how vulnerable our body can really become once the barrier has been broken and permeability becomes an issue.

  • “Intestinal barrier” is a term that has been established more recently by gastroenterologists, immunologists and microbiologists to emphasize the protective component of the gut shielding us against bacterial invasion, or invasion of other microorganisms and their toxins
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